Recent advances in trypanosomatid research: genome organization, expression, metabolism, taxonomy and evolution

0519991 - BC 2020 RIV GB eng J - Článek v odborném periodiku
Maslov, D. A. - Opperdoes, F. R. - Kostygov, A. Y. - Hashimi, Hassan - Lukeš, Julius - Yurchenko, Vyacheslav
Recent advances in trypanosomatid research: genome organization, expression, metabolism, taxonomy and evolution.
Parasitology. Roč. 146, č. 1 (2019), s. 1-27. ISSN 0031-1820. E-ISSN 1469-8161
Grant CEP: GA ČR(CZ) GA16-18699S; GA ČR GA17-24036S; GA ČR(CZ) GA18-15962S; GA MŠMT(CZ) LL1601; GA MŠMT(CZ) EF16_019/0000759
Institucionální podpora: RVO:60077344
Klíčová slova: rna gene-transcription * kinetoplast maxicircle dna * predominant clonal evolution * edited messenger-rnas * toads bufo-americanus * class-i transcription * cytochrome-c-oxidase * multiple guide rnas * sp n. kinetoplastea * life-cycle stages * Gene exchange * kinetoplast * metabolism * molecular and cell biology * taxonomy * trypanosomatidae
Obor OECD: Biochemical research methods
Impakt faktor: 2.783, rok: 2019
Způsob publikování: Open access
https://www.cambridge.org/core/journals/parasitology/article/recent-advances-in-trypanosomatid-research-genome-organization-expression-metabolism-taxonomy-and-evolution/0B71FE52E53074DF5C82D03FF236ACFE

Unicellular flagellates of the family Trypanosomatidae are obligatory parasites of invertebrates, vertebrates and plants. Dixenous species are aetiological agents of a number of diseases in humans, domestic animals and plants. Their monoxenous relatives are restricted to insects. Because of the high biological diversity, adaptability to dramatically different environmental conditions, and omnipresence, these protists have major impact on all biotic communities that still needs to be fully elucidated. In addition, as these organisms represent a highly divergent evolutionary lineage, they are strikingly different from the common 'model system' eukaryotes, such as some mammals, plants or fungi. A number of excellent reviews, published over the past decade, were dedicated to specialized topics from the areas of trypanosomatid molecular and cell biology, biochemistry, host-parasite relationships or other aspects of these fascinating organisms. However, there is a need for a more comprehensive review that summarizing recent advances in the studies of trypanosomatids in the last 30 years, a task, which we tried to accomplish with the current paper.
Trvalý link: http://hdl.handle.net/11104/0304856