High Frequency QRS Analysis from Orthogonal Leads

0509022 - ÚPT 2020 RIV US eng C - Konferenční příspěvek (zahraniční konf.)
Halámek, Josef - Leinveber, P. - Malik, M. - Schmidt, G. - Plešinger, Filip - Matějková, M. - Lipoldová, J. - Jurák, Pavel
High Frequency QRS Analysis from Orthogonal Leads.
Computing in Cardiology 2018. Vol. 45. New York: IEEE, 2018, č. článku 8743704. E-ISSN 2325-887X.
[Computing in Cardiology Conference (CinC) /45./. Maastricht (NL), 23.09.2018-26.09.2018]
Grant CEP: GA ČR GA17-13830S; GA MŠMT(CZ) LO1212
Institucionální podpora: RVO:68081731
Klíčová slova: high frequency HF * dilated cardiomyopathy * ECG
Obor OECD: Cardiac and Cardiovascular systems

We analysed high frequency averaged QRS (HFQRS) in orthogonal leads and different passbands. Three groups of subjects were compared: healthy subjects, ischemic heart disease (IHD) and dilated cardiomyopathy (DCM) patients. Among the IHD group, those with heart failure (HF) symptoms were identified. Investigated parameters included HFQRS maximal amplitude, HFQRS power, and HFQRS fragmentation based on normalized length of the HFQRS line. The study aimed at assessing (1) group differences in relation to the passband, lead, and parameter, and (2) the reproducibility of parameters.
Results: Significant differences were found between healthy subjects and IHD or DCM in all parameters and passbands. Some singularities of significance existed between IHD and DCM. Significant differences were also found between IHD sub-groups with and without HF symptoms, and these existed over more frequency bands.
Conclusion: HFQRS parameters are frequency dependent and this dependency should be tested to eliminate singularities in statistical significances. Differences between groups with or without HF symptoms were found mainly at higher passbands, regardless of deterioration of reproducibility. Lead X appeared to be the lead with maximal differences between groups.
Trvalý link: http://hdl.handle.net/11104/0299836