Experimental and Theoretical Perspectives of the Noyori-Ikariya Asymmetric Transfer Hydrogenation of Imines

0506837 - MBÚ 2020 RIV CH eng J - Článek v odborném periodiku
Václavík, J. - Šot, P. - Pecháček, J. - Vilhanová, B. - Matuška, O. - Kuzma, Marek - Kačer, P.
Experimental and Theoretical Perspectives of the Noyori-Ikariya Asymmetric Transfer Hydrogenation of Imines.
Molecules. Roč. 19, č. 6 (2014), s. 6987-7007. E-ISSN 1420-3049
Grant CEP: GA ČR GAP106/12/1276; GA MŠMT(CZ) LO1509
Výzkumná infrastruktura: CESNET - 90005
Institucionální podpora: RVO:61388971
Klíčová slova: ruthenium * asymmetric hydrogenation * imine
Obor OECD: Microbiology
Impakt faktor: 2.416, rok: 2014
Způsob publikování: Open access
https://www.mdpi.com/1420-3049/19/6/6987

The asymmetric transfer hydrogenation (ATH) of imines catalyzed by the Noyori-Ikariya [RuCl(eta(6)-arene)(N-arylsulfonyl-DPEN)] (DPEN = 1,2-diphenylethylene-1,2- diamine) half-sandwich complexes is a research topic that is still being intensively developed. This article focuses on selected aspects of this catalytic system. First, a great deal of attention is devoted to the N-arylsulfonyl moiety of the catalysts in terms of its interaction with protonated imines (substrates) and amines (components of the hydrogen-donor mixture). The second part is oriented toward the role of the eta(6)-coordinated arene. The final part concerns the imine substrate structural modifications and their importance in connection with ATH. Throughout the text, the summary of known findings is complemented with newly-presented ones, which have been approached both experimentally and computationally.
Trvalý link: http://hdl.handle.net/11104/0297987