Effect of Thymine and Cytosine Nucleobase Sequence on the Two-Dimensional Condensation of Pyrimidine Oligodeoxynucleotides at Mercury Surface

0506653 - BFÚ 2020 RIV CZ eng C - Konferenční příspěvek (zahraniční konf.)
Hasoň, Stanislav - Fojta, Miroslav
Effect of Thymine and Cytosine Nucleobase Sequence on the Two-Dimensional Condensation of Pyrimidine Oligodeoxynucleotides at Mercury Surface.
XXXVII. Moderní elektrochemické metody. Sborník přednášek mezinárodní odborné konference. Ústí nad Labem: Best servis, 2017 - (Navrátil, T.; Fojta, M.; Schwarzová, K.), Č. 2017 (2017), s. 50-54. ISBN 978-80-905221-5-2.
[Moderní elektrochemické metody /37./. Jetřichovice (CZ), 15.05.2017-19.05.2017]
Grant CEP: GA ČR(CZ) GA16-01625S; GA MŠMT EF15_003/0000477
Institucionální podpora: RVO:68081707
Klíčová slova: phase transients * water interface * nucleic-acids * adsorption
Obor OECD: Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

The aim of this contribution is study the effect of thymine and cytosine nucleobase composition (different lengths and/or repeat segments of either thymine or cytosine units or their combinations) within a set of the oligodeoxynucleotide (ODN) chains on the two-dimensional of homo- and hetero-pyrimidine ODNs at mercury electrode surface. It was shown that pyrimidine ODNs containing eight and more pyrimidine nucleobases can form, at negatively charged Hg surface (around1.32 V vs. Ag/AgCl), two different 2D condensed films characterized by the differential capacitances of about 9.4 (I-2D) and 7.6 mu F cm(-2) (II2D) respectively.
Trvalý link: http://hdl.handle.net/11104/0297858