Water-soluble Re6-clusters with aromatic phosphine ligands – from synthesis to potential biomedical applications

0503913 - ÚACH 2020 RIV GB eng J - Článek v odborném periodiku
Ivanov, A. A. - Konovalov, D.I. - Pozmogova, T.N. - Solovieva, A.O. - Melnikov, A. - Brylev, K. A. - Kuratieva, N.V. - Yanshole, V.V. - Kirakci, Kaplan - Lang, Kamil - Cheltygmasheva, S.N. - Kitamura, N. - Shestopalova, L.V. - Mironov, Y.V. - Shestopalov, M.A.
Water-soluble Re6-clusters with aromatic phosphine ligands – from synthesis to potential biomedical applications.
Inorganic Chemistry Frontiers. Roč. 6, č. 4 (2019), s. 882-892. ISSN 2052-1553. E-ISSN 2052-1553
Grant CEP: GA ČR(CZ) GA18-05076S
Institucionální podpora: RVO:61388980
Klíčová slova: hexarhenium clusters * rhenium clustert complexes * supramolecular arrays
Obor OECD: Inorganic and nuclear chemistry
Impakt faktor: 5.958, rok: 2019
Způsob publikování: Omezený přístup
https://pubs.rsc.org/en/content/articlelanding/2019/QI/C8QI01216D#!divAbstract

The development of water-soluble hexanuclear cluster complexes of low toxicity is a promising task due to their potential biomedical applications such as bioimaging and photodynamic therapy. Herein, we present the syntheses of two new water-soluble hexarhenium cluster complexes with terminal amphiphilic phosphine ligands, and delineate their photoluminescence and X-ray excited optical luminescence (XEOL) properties. These cluster complexes, namely [{Re6Q8}(PPh2CH2CH2COO)6] 4− (Q = S (1), Se, (2)), have the least cytotoxicity among all the tested hexanuclear metal-clusters, are capable of penetrating into cells and exhibit moderate photodynamic toxicity toward Hep-2 cells.
Trvalý link: http://hdl.handle.net/11104/0296575


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