The Effect of Selected Feed Mixtures on the Duodenal Morphology: Comparison Study

0502266 - ÚMG 2019 RIV CZ eng J - Článek v odborném periodiku
Makovický, Peter - Chrenková, M. - Makovický, P. - Flak, P. - Formelová, Z. - Novosadová, Vendula - Rajský, M. - Vannucci, Luca
The Effect of Selected Feed Mixtures on the Duodenal Morphology: Comparison Study.
Physiological Research. Roč. 67, č. 6 (2018), s. 955-962. ISSN 0862-8408. E-ISSN 1802-9973
Grant CEP: GA MŠMT(CZ) ED1.1.00/02.0109
Institucionální podpora: RVO:68378050 ; RVO:61388971
Klíčová slova: Celiac disease * Gluten-free diet * Cereals * Nutrition * Villi intestinalis
Obor OECD: Biochemistry and molecular biology; Immunology (MBU-M)
Impakt faktor: 1.701, rok: 2018

The objective of this work was to compare the effect of selected feed mixtures on the duodenal morphology. One-hundred-four rats of the Wistar strain were divided to thirteen groups per eight rats. The experiment started in 35-day-old rats after birth and lasted for 32 days. The groups (A-M) were fed by commercial diet, 85 % wheat and 15 % oat diet, 85 % wheat and 15 % triticale, 85 % wheat and 15 % barley, 85 % wheat and 15 % amaranth, 85 % wheat and 15 % lantern, 85 % wheat and 15 % buckwheat, 100 % wheat, 100 % white lupine, 100 % flock peas variety Garden, 100 % native peas variety Garden, 100 % native peas variety Zekon or 100 % extruded peas variety Zekon diet, respectively. Samples from the duodenum were taken. The height of the villi and the depth of the crypts were measured. The tallest villi were measured in group F (474.33 +/- 114.36 mu m) and the shortest villi were observed in group B (294.08 +/- 88.52 mu m). The deepest crypts were measured in group K (166.41 +/- 35.69 mu m) and the shallowest crypts were observed in group E (77.85 +/- 17.61 mu m). The work documents that gluten-free and classical cereals combination can be a better choice for people who want to limit the gluten content of the diet.
Trvalý link: http://hdl.handle.net/11104/0294211