Laser-accelerated proton beams from a solid hydrogen target as a future source of radionuclides for positron emission tomography

0501410 - FZÚ 2019 RIV IN eng J - Článek v odborném periodiku
Italiano, A. - Amato, E. - Margarone, Daniele - Pšikal, Jan - Korn, Georg
Laser-accelerated proton beams from a solid hydrogen target as a future source of radionuclides for positron emission tomography.
Journal of Scientific and Engineering Research. Roč. 4, č. 11 (2017), s. 173-176. E-ISSN 2394-2630
Grant CEP: GA MŠMT EF16_019/0000789; GA MŠMT LQ1606
Grant ostatní: OP VVV - ADONIS(XE) CZ.02.1.01/0.0/0.0/16_019/0000789
Institucionální podpora: RVO:68378271
Klíčová slova: laser * particle acceleration * positron emission tomography * Extreme Laser Infrastructure
Obor OECD: Fluids and plasma physics (including surface physics)
http://jsaer.com/archive/volume-4-issue-11-2017

The production of radionuclides for positron emission tomography through future laser-accelerated proton beams is an interesting perspective. We evaluated the production yields that can be expected according to a new source term based on three-dimensional particle-in-cell (PIC) simulations of the laser available at ELI-Beamlines interacting with an innovative cryogenic hydrogen target. Results indicate that 370 MBq activity can be reached within a few minutes of irradiation for the four conventional PET nuclides 18F, 11C, 13N and 15O, and for several heavier positron emitters, such as 60Cu, 62Cu, 63Zn, 68Ga and 73Se, currently used in pre-clinical and clinical studies.
Trvalý link: http://hdl.handle.net/11104/0293446