Electromagnetic fields and optomechanics in cancer diagnostics and treatment

0499918 - ÚFE 2019 RIV US eng J - Článek v odborném periodiku
Salari, V. - Barzanjeh, Sh. - Cifra, Michal - Simon, C. - Scholkmann, F. - Alirezaei, Z. - Tuszyński, J.A.
Electromagnetic fields and optomechanics in cancer diagnostics and treatment.
Frontiers in Bioscience. Roč. 23, č. 8 (2018), s. 1391-1406. ISSN 1093-9946. E-ISSN 1093-4715
Grant CEP: GA ČR(CZ) GA15-17102S; GA ČR(CZ) GA17-11898S
Grant ostatní: AV ČR(CZ) SAV-15-22
Program: Bilaterální spolupráce
Institucionální podpora: RVO:67985882
Klíčová slova: Electromagnetic fields * Cancer * Microtubule
Obor OECD: Electrical and electronic engineering
Impakt faktor: 2.214, rok: 2018

In this paper, we discuss biological effects of electromagnetic (EM) fields in the context of cancer biology. In particular, we review the nanomechanical properties of microtubules (MTs), the latter being one of the most successful targets for cancer therapy. We propose an investigation on the coupling of electromagnetic radiation to mechanical vibrations of MTs as an important basis for biological and medical applications. In our opinion, optomechanical methods can accurately monitor and control the mechanical properties of isolated MTs in a liquid environment. Consequently, studying nanomechanical properties of MTs may give useful information for future applications to diagnostic and therapeutic technologies involving non-invasive externally applied physical fields. For example, electromagnetic fields or high intensity ultrasound can be used therapeutically avoiding harmful side effects of chemotherapeutic agents or classical radiation therapy
Trvalý link: http://hdl.handle.net/11104/0292105