Evaluation of dynamic DCE-MRI of the temporomandibular joint

0495725 - ÚPT 2019 US eng A - Abstrakt
Macíček, Ondřej - Andersen, E. - Angenete, O. - Augdal, T. A. - Rosendahl, K. - Jiřík, Radovan - Grüner, R.
Evaluation of dynamic DCE-MRI of the temporomandibular joint.
Joint Annual Meeting ISMRM-ESMRMB 2018. Book of Absdtracts.. Concord: ISMRM, 2018.
[Joint Annual Meeting ISMRM-ESMRMB 2018. 16.06.2018-18.06.2018, Paris]
Grant CEP: GA ČR(CZ) GA16-13830S; GA MŠMT(CZ) LO1212; GA MŠMT(CZ) EF16_013/0001775
Institucionální podpora: RVO:68081731
Klíčová slova: DCE-MRI * TMJ * deconvolution
Obor OECD: Medical engineering

The feasibility of DCE-MRI as a tool to investigate perfusion of temporomandibular joints (TMJs) in case of Juvenile Idiopathic Arthritis (JIA) in children is investigated. The hypothesis in this current study is that inflammation is associated with increased
vascularity and is the origin of experienced pain. Contrary to previous studies, high temporal resolution (~4s) dynamic DCE-MRI using advanced pharmacokinetic models are for the first time applied when imaging the TMJ in JIA children aged 6-15.
Results of deconvolution show that there is a difference in perfusion parameters between affected and unaffected patients, especially when permeability-surface area product (PS) and blood plasma flow (Fp) parameters are combined.
Trvalý link: http://hdl.handle.net/11104/0288654