Resveratrol, pterostilbene, and baicalein: plant-derived anti-biofilm agents.

0493464 - MBÚ 2019 RIV CZ eng J - Článek v odborném periodiku
Kolouchová, I. - Maťáková, O. - Paldrychová, M. - Kodeš, Z. - Kvasničková, E. - Sigler, Karel - Čejková, A. - Šmidrkal, J. - Demnerová, K. - Masák, J.
Resveratrol, pterostilbene, and baicalein: plant-derived anti-biofilm agents.
Folia Microbiologica. Roč. 63, č. 3 (2018), s. 261-272. ISSN 0015-5632. E-ISSN 1874-9356
Institucionální podpora: RVO:61388971
Klíčová slova: Baicalein * Resveratrol * Pterostilbene
Obor OECD: Microbiology
Impakt faktor: 1.448, rok: 2018

Microbial adhesion to surfaces and the subsequent biofilm formation may result in contamination in food industry and in healthcare-associated infections and may significantly affect postoperative care. Some plants produce substances with antioxidant and antimicrobial properties that are able to inhibit the growth of food-borne pathogens. The aim of our study was to evaluate antimicrobial and anti-biofilm effect of baicalein, resveratrol, and pterostilbene on Candida albicans, Staphylococcus epidermidis, Pseudomonas aeruginosa, and Escherichia coli. We determined the minimum inhibitory concentrations (MIC), the minimum adhesion inhibitory concentration (MAIC), and the minimum biofilm eradication concentration (MBEC) by crystal violet and XTT determination. Resveratrol and pterostilbene have been shown to inhibit the formation of biofilms as well as to disrupt preformed biofilms. Our results suggest that resveratrol and pterostilbene appear potentially very useful to control and inhibit biofilm contaminations by Candida albicans, Staphylococcus epidermidis, and Escherichia coli in the food industry.
Trvalý link: http://hdl.handle.net/11104/0286833