Proteomic profile in human breast carcinoma MDA-MB-231 cells induced by tributyltin isothiocyanate, the biologically active ligand of nuclear retinoid X receptors

0491824 - ÚIACH 2019 FR eng A - Abstrakt
Brtko, J. - Strouhalová, Dana - Toporová, L. - Macejová, D. - Bobál, P. - Otevřel, J. - Bobálová, Janette
Proteomic profile in human breast carcinoma MDA-MB-231 cells induced by tributyltin isothiocyanate, the biologically active ligand of nuclear retinoid X receptors.
RICT 2018. Book of Abstracts. Société de Chimie Thérapeutique, 2018. s. 131.
[RICT 2018. International Conference on Medicinal Chemistry /54./. 04.07.2018-06.07.2018, Strasbourg]
Grant ostatní: AV ČR(CZ) SAV-18-16
Program: Bilaterální spolupráce
Institucionální podpora: RVO:68081715
Klíčová slova: human breast * proteomic profile * X receptors
Obor OECD: Analytical chemistry

The aim of this study was to investigate the effect of biologically active ligand of nuclear retinoid/retinoid X receptors of natural origin all-trans retinoic acid (RAR ligand) and freshly synthesized (commercially non-accessible) tributyltin isothiocyanate, synthetic RXR ligand and their combination on protein profile.
Trvalý link: http://hdl.handle.net/11104/0285441