Enantioselective Complexation of 1‐Phenylethanol with Chiral Compounds Bearing Urea Moiety.

0490484 - ÚCHP 2019 RIV US eng J - Článek v odborném periodiku
Cuřínová, Petra - Dračínský, Martin - Jakubec, Martin - Tlustý, M. - Janků, K. - Izák, Pavel - Holakovský, R.
Enantioselective Complexation of 1‐Phenylethanol with Chiral Compounds Bearing Urea Moiety.
Chirality. Roč. 30, č. 6 (2018), s. 798-806. ISSN 0899-0042. E-ISSN 1520-636X
Grant CEP: GA ČR(CZ) GA17-00089S; GA ČR(CZ) GA18-11851S
Institucionální podpora: RVO:67985858 ; RVO:61388963
Klíčová slova: enantioselective complexation * binaphthalene * urea
Obor OECD: Physical chemistry; Organic chemistry (UOCHB-X)
Impakt faktor: 1.927, rok: 2018

A detailed study of diastereomeric complexes of chiral ureido-1,1′-binaphthalene derivatives with chiral 1-phenylethanol showed that a derivative bearing only one urea unit makes five times more stable complex with (S)-enantiomer than with (R)-enantiomer of the alcohol. This phenomenon could be used in chiral discrimination processes. The influence of individual parts of the structure on the complexation properties is shown. The probable structure of diastereomeric complexes based on experimental results and computational methods is proposed.
Trvalý link: http://hdl.handle.net/11104/0284712