Počet záznamů: 1
2-Bromo[6]helicene as a Key Intermediate for [6]Helicene Functionalization.
- 1.0488982 - ÚCHP 2019 RIV US eng J - Článek v odborném periodiku
Jakubec, Martin - Beránek, Tomáš - Jakubík, Pavel - Sýkora, Jan - Žádný, Jaroslav - Církva, Vladimír - Storch, Jan
2-Bromo[6]helicene as a Key Intermediate for [6]Helicene Functionalization.
Journal of Organic Chemistry. Roč. 83, č. 7 (2018), s. 3607-3616. ISSN 0022-3263. E-ISSN 1520-6904
Grant CEP: GA ČR GA15-12719S
Institucionální podpora: RVO:67985858
Klíčová slova: helicene * racemization barrier * enantiomers
Obor OECD: Organic chemistry
Impakt faktor: 4.745, rok: 2018
The synthesis of 2-bromo[6]helicene was revised and improved up to 51% yield. Its reactivity was thoroughly investigated, and a library of 17 different carbon, boron, nitrogen, phosphorus, oxygen and sulfur substituted derivatives was prepared. The racemization barrier for 2-bromo[6]helicene was determined, and the usage of enantiomers in the synthesis of optically pure helicenes was rationalized. The three most energy-demanding reactions using enantiomerically pure 2-bromo[6]helicene were tested in order to confirm the predicted enantiomeric excess.
Trvalý link: http://hdl.handle.net/11104/0283624
Počet záznamů: 1