Počet záznamů: 1
LESM: a laser-driven sub-MeV electron source delivering ultra-high dose rate on thin biological samples
- 1.0488211 - FZÚ 2018 RIV GB eng J - Článek v odborném periodiku
Labate, L. - Andreassi, M.G. - Baffigi, F. - Bizzarri, B.M. - Borghini, A. - Bussolino, G.C. - Fulgentini, L. - Ghetti, F. - Giulietti, A. - Köster, P. - Lamia, D. - Levato, Tadzio - Oishi, Y. - Pulignani, S. - Russo, G. - Sgarbossa, A. - Gizzi, L.A.
LESM: a laser-driven sub-MeV electron source delivering ultra-high dose rate on thin biological samples.
Journal of Physics D-Applied Physics. Roč. 49, č. 27 (2016), s. 1-9, č. článku 275401. ISSN 0022-3727. E-ISSN 1361-6463
Grant CEP: GA MŠMT EF15_008/0000162; GA MŠMT LQ1606
Grant ostatní: ELI Beamlines(XE) CZ.02.1.01/0.0/0.0/15_008/0000162
Institucionální podpora: RVO:68378271
Klíčová slova: laser-driven electron accelerators * sub-MeV electron sources * ultrahigh dose rate * radiobiology * cell radiation damage
Obor OECD: Fluids and plasma physics (including surface physics)
Impakt faktor: 2.588, rok: 2016
We present a laser-driven source of electron bunches with average energy 260 keV and picosecond duration, which has been setup for radiobiological tests covering the previously untested sub-MeV energy range. Each bunch combines high charge with short duration and sub-millimeter range into a record instantaneous dose rate, as high as 10(9) Gy s(-1). The source can be operated at 10 Hz and its average dose rate is 35 mGy s(-1). Both the high instantaneous dose rate and high level of relative biological effectiveness, attached to sub-MeV electrons, make this source very attractive for studies of ultrafast radiobiology on thin cell samples. The source reliability, in terms of shot-to-shot stability of features such as mean energy, bunch charge and transverse beam profile, is discussed, along with a dosimetric characterization. Finally, a few preliminary biological tests performed with this source are presented.
Trvalý link: http://hdl.handle.net/11104/0282811
Počet záznamů: 1