Occurrence of pharmaceuticals, illicit drugs, and resistant types of bacteria in hospital effluent and their effective degradation by boron-doped diamond electrodes

0486145 - FZÚ 2018 RIV AT eng J - Článek v odborném periodiku
Mackuľak, T. - Vojs, M. - Grabic, R. - Golovko, O. - Staňová, A. - Birošová, L. - Medveďová, A. - Híveš, J. - Gál, M. - Kromka, Alexander - Hanusová, A.
Occurrence of pharmaceuticals, illicit drugs, and resistant types of bacteria in hospital effluent and their effective degradation by boron-doped diamond electrodes.
Monatshefte fur Chemie. Roč. 147, č. 1 (2016), s. 93-103. ISSN 0026-9247. E-ISSN 1434-4475.
[35th International Conference on Modern Electrochemical Methods (MEM). Jetřichovice, 18.05.2015-22.05.2015]
Institucionální podpora: RVO:68378271
Klíčová slova: hospital wastewater * antibiotics * ecology * boron-doped diamond electrode * mass spectroscopy * pharmaceuticals
Obor OECD: Condensed matter physics (including formerly solid state physics, supercond.)
Impakt faktor: 1.282, rok: 2016

In this study, we have investigated the composition of wastewaters from two Slovak and one Czech hospital. Using in-line solid phase extraction liquid chromatography coupled with tandem mass spectrometry (in-line-SPE-LC-MS/MS), we monitored the occurrence of 29 pharmaceuticals, illegal drugs and their metabolites and resistant types of microorganisms. It was found that cotinine (max 1980 ng/dm(3)), tramadol (max 1570 ng/dm(3)), venlafaxine (max 248 ng/dm(3)), codeine (max 136 ng/dm(3)), oxazepam (max 113 ng/dm(3)), and oxycodone (max 102 ng/dm(3)) belong to the group of the most concentrated compounds. The number of coliform bacteria ranged from 5.5 to 7 log CFU/cm(3), while majority of strains were ampicillin, gentamicin, and ciprofloxacin resistant. The number of Staphylococcus aureus was lower (2.7-3.8 log CFU/cm(3)), with predominance of ampicillin and penicillin resistants.

Trvalý link: http://hdl.handle.net/11104/0281007