Optimizing and Evaluating the Biocompatibility of Fiber Composites with CaP Additives

0485392 - ÚSMH 2018 CZ eng C - Konferenční příspěvek (zahraniční konf.)
Suchý, Tomáš - Sucharda, Zbyněk - Balík, Karel - Sochor, M. - Bačáková, Lucie
Optimizing and Evaluating the Biocompatibility of Fiber Composites with CaP Additives.
International Conference of the Czech Society of Biomechanics - Human Biomechanics 2010. Liberec: Technická univerzita Liberec, 2010 - (Čapek, L.), s. 323-328. ISBN 978-80-7372-648-5.
[International Conference of the Czech-Society-of-Biomechanics on Human Biomechanics 2010. Sychrov (CZ), 04.10.2010-06.10.2010]
Grant CEP: GA ČR(CZ) GA106/06/1576; GA ČR(CZ) GAP108/10/1457
Výzkumný záměr: CEZ:AV0Z30460519; CEZ:AV0Z50110509
Klíčová slova: biocomposites * calcium phosphate * polyamide fibers * polydimethylsiloxane
Obor OECD: Composites (including laminates, reinforced plastics, cermets, combined natural and synthetic fibre fabrics

Composite materials based on a polyamide fabric (aramid) and a polydymethyl-siloxane (PDMS) matrix were designed for application in bone surgery. In order to increase the bioactivity, 2, 5, 10, 15, 20 and 25 vol. % of nano/micro hydroxyapatite (HA) and tricalcium phosphate (TCP) were added. The effect of the additives on the biocompatibility was studied. It appears that nano additives have a more favorable effect than micro particles on mechanical properties. For final application of the composites as substitutes for bone tissues, 15 vol. % of nano hydroxyapatite additives is an optimum amount: in this case both the mechanical properties and the biological properties are optimized without distinct changes in the inner structure of the composite.
Trvalý link: http://hdl.handle.net/11104/0280427