Počet záznamů: 1
Oxidative stress in primary porcine fibroblasts expressing mutated huntingtin
- 1.0485171 - ÚŽFG 2018 CZ eng K - Konferenční příspěvek (tuzemská konf.)
Šmatlíková, Petra - Askeland, G. - Vaškovičová, Michaela - Klíma, Jiří - Motlík, Jan - Eide, L. - Ellederová, Zdeňka
Oxidative stress in primary porcine fibroblasts expressing mutated huntingtin.
The 4th Animal Models of Neurodegenerative Diseases. Liběchov: ÚŽFG AV ČR, v. v. i., 2017, s. 28-29.
[Animal Models of Neurodegenerative Diseases /4./. Liblice (CZ), 22.10.2017-24.10.2017]
Grant CEP: GA MŠMT(CZ) LO1609
Institucionální podpora: RVO:67985904
Klíčová slova: huntingtin
Obor OECD: Cell biology
Molecular events, such as protein aggregation, mitochondrial dysfunction, and transcriptional dysregulation have been linked to Huntington’s disease (HD) pathogenesis. Oxidative stress has been considered as one of the key players in disease progression. Though, it is still not clear whether oxidative stress causes HD, or if it is a consequence of other primary events.
Trvalý link: http://hdl.handle.net/11104/0280248
Počet záznamů: 1