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Letter to the Editor. Acetic acid is elevated in the exhaled breath of cystic fibrosis patients

  1. 1. 0484021 - UFCH-W 2018 RIV NL eng J - Článek v odborném periodiku
    Španěl, Patrik - Sovová, Kristýna - Dryahina, Kseniya - Doušová, T. - Dřevínek, P. - Smith, D.
    Letter to the Editor. Acetic acid is elevated in the exhaled breath of cystic fibrosis patients.
    Journal of Cystic Fibrosis. Roč. 16, č. 5 (2017), e17-e18 ISSN 1569-1993
    Grant CEP: GA ČR(CZ) GA14-14534S
    Institucionální podpora: RVO:61388955
    Klíčová slova: acetic acid * cystic fibrosis transmembrane conductance regulator * volatile organic compound
    Kód oboru RIV: CB - Analytická chemie, separace
    Obor OECD: Analytical chemistry
    Impakt faktor: 3.858, rok: 2017

    Breath analysis is becoming an attractive non-invasive aid to
    clinical diagnosis and therapeutic monitoring and can provide
    more insight into pathology of cystic fibrosis (CF) and related
    respiratory infections. Selected ion flow tube mass spectrometry,
    SIFT-MS [1] allows the analysis of single breath
    exhalations on line and also by the off-line analysis of breath
    samples collected into bags. SIFT-MS breath analysis has been
    directed previously towards identification of volatile biomarkers
    of bacterial infection, including Pseudomonas
    aeruginosa that commonly infect the lungs of CF patients.
    Thus, hydrogen cyanide, HCN, has been identified as a breath
    metabolite compound specific (99%) to P. aeruginosa [2].
    Trvalý link: http://hdl.handle.net/11104/0279181
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