Počet záznamů: 1
Controlling complexity: the clinical relevance of mouse complex genetics
- 1.0483191 - ÚMG 2018 RIV GB eng J - Článek v odborném periodiku
Forejt, Jiří … celkem 50 autorů
Controlling complexity: the clinical relevance of mouse complex genetics.
European Journal of Human Genetics. Roč. 21, č. 11 (2013), s. 1191-1196. ISSN 1018-4813. E-ISSN 1476-5438
Institucionální podpora: RVO:68378050
Klíčová slova: Mouse model * Forward genetics * Rewiev
Obor OECD: Genetics and heredity (medical genetics to be 3)
Impakt faktor: 4.225, rok: 2013
Experimental animal models are essential to obtain basic knowledge of the underlying biological mechanisms in human diseases. Here, we review major contributions to biomedical research and discoveries that were obtained in the mouse model by using forward genetics approaches and that provided key insights into the biology of human diseases and paved the way for the development of novel therapeutic approaches.
Trvalý link: http://hdl.handle.net/11104/0278582
Počet záznamů: 1