Joint DCE- and DSC-MRI processing using the Gradient correction model

0481385 - ÚPT 2018 US eng A - Abstrakt
Macíček, Ondřej - Jiřík, Radovan - Starčuk jr., Zenon
Joint DCE- and DSC-MRI processing using the Gradient correction model.
Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM). Vol. 25. Berkeley: International Society of Magnetic Resonance, 2017. s. 1901. ISSN 1545-4428.
[ISMRM. Annual Meeting and Exhibition /25./. 22.04.2017-27.04.2017, Honolulu]
Grant CEP: GA ČR(CZ) GA16-13830S; GA MŠMT(CZ) LO1212
Institucionální podpora: RVO:68081731
Klíčová slova: DCE- and DSC-MRI * Gradient correction model
Obor OECD: Medical engineering

The contribution presents a method for simultaneous processing of the DCE- and DSC-MRI perfusion data acquired using a multi-echo sequence. It is an extension of the sequential application of the so-called gradient correction model. In the sequential approach, relaxivity parameters are estimated from the DSC signal based on perfusion parameters calculated from the DCE signal. Here the perfusion and relaxivity parameters are estimated using an iterative alternating optimization strategy. The impact on accuracy and precision is tested on synthetic data. The results show that the suggested approach can yield a remarkable improvement, especially for noisy data.
Trvalý link: http://hdl.handle.net/11104/0276960