Prompt gamma-ray emission for future imaging applications in proton-boron fusion therapy

0480147 - FZÚ 2018 RIV GB eng J - Článek v odborném periodiku
Petringa, G. - Cirrone, G. A. P. - Caliri, C. - Cuttone, G. - Giuffrida, Lorenzo - La Rosa, G. - Manna, R. - Manti, L. - Marchese, V. - Marchetta, C. - Margarone, Daniele - Milluzzo, G. - Picciotto, A. - Romano, F. - Romano, F.P. - Russo, A.D. - Russo, G. - Santonocito, D. - Scuderi, Valentina
Prompt gamma-ray emission for future imaging applications in proton-boron fusion therapy.
Journal of Instrumentation. Roč. 12, Mar (2017), s. 1-4, č. článku C03059. ISSN 1748-0221. E-ISSN 1748-0221
Grant CEP: GA MŠMT EF15_008/0000162; GA MŠMT LQ1606
Grant ostatní: ELI Beamlines(XE) CZ.02.1.01/0.0/0.0/15_008/0000162
Institucionální podpora: RVO:68378271
Klíčová slova: instrumentation for particle-beam therapy * targets * spallation source targets * radioisotope production * neutrino and muon sources
Obor OECD: Fluids and plasma physics (including surface physics)
Impakt faktor: 1.258, rok: 2017

Recently, an approach exploiting the proton therapy biological enhancement by using Boron atoms injected inside a tumor, has been proposed [1-3]. Here, the B-11( p,alpha)2 alpha nuclear fusion reaction channel, where three alpha particles are produced with an average energy around 4MeV, is considered [4]. These alphas are able to penetrate the cells nucleus and strongly damage their DNA. In addition, gamma prompts emitted by the proton Boron nuclear reactions can be used for on-line proton beam imaging purposes.
Trvalý link: http://hdl.handle.net/11104/0276055