In-line coupling of supported liquid membrane extraction to capillary electrophoresis for simultaneous analysis of basic and acidic drugs in urine

0478346 - ÚIACH 2018 RIV NL eng J - Článek v odborném periodiku
Pantůčková, Pavla - Kubáň, Pavel
In-line coupling of supported liquid membrane extraction to capillary electrophoresis for simultaneous analysis of basic and acidic drugs in urine.
Journal of Chromatography A. Roč. 1519, OCT (2017), s. 137-144. ISSN 0021-9673. E-ISSN 1873-3778
Grant CEP: GA ČR(CZ) GA16-09135S
Institucionální podpora: RVO:68081715
Klíčová slova: supported liquid membrane extraction * capillary electrophoresis * in-line sample treatment
Obor OECD: Analytical chemistry
Impakt faktor: 3.716, rok: 2017

Simultaneous extraction of basic and acidic drugs across thin supported liquid membrane (SLM) and direct injection of the extracted drugs from SLM surface into capillary electrophoresis (CE) were demonstrated. The analytical method was suitable for simultaneous determination of both groups of drugs in undiluted human urine and was used for direct determination of naproxen in urine after oral administration of Nalgesin S tablet.
Trvalý link: http://hdl.handle.net/11104/0274443