Mechanism of complex tooth shape development in reptiles

0476477 - ÚŽFG 2018 CZ eng K - Konferenční příspěvek (tuzemská konf.)
Landová, Marie - Zahradníček, Oldřich - Dosedělová, Hana - Kavková, M. - Zikmund, T. - Buchtová, Marcela
Mechanism of complex tooth shape development in reptiles.
YGVA - Proceedings of the 9th meeting of the young generation of veterinary anatomists. Brno: VFU Brno, 2017, s. 38-40. ISBN N.
[Meeting of the Young Generation of Veterinary Anatomists /9./. Brno (CZ), 12.07.2017-14.07.2017]
Grant CEP: GA ČR(CZ) GB14-37368G; GA MŠMT EF15_003/0000460
Institucionální podpora: RVO:67985904 ; RVO:68378041
Klíčová slova: reptiles * tooth shape development
Obor OECD: Developmental biology

Tooth shape formation in mammals is well known proces thanks to the broad studies on the mouse molars. The main role in regulation of this proces plays the enamel knot. Enamel knots are formed by cluster of cells, which serves as a source of numerous signalling molecules such as SHH or members of WNT, BMP and FGF families. Almost all our knowledge about teeth came from study on the mouse model. For better understanding of odontogenesis, it is however necessary to compare developmental processes to another species. One of the most heterogenic group of dentition type and shape are reptiles. How the shape of their teeth completed is still unknown. Aim of our study is therefore to uncover developmental processes involved in cusp formation in non-mammalian species with focus on reptiles. As model species for this study, we selected chameleons where multicuspis teeth develop in the caudal area of the jaw.
Trvalý link: http://hdl.handle.net/11104/0272966