Photosynthesis-Inhibiting Activity of 1-[(2-Chlorophenyl)carbamoyl]- and 1-[(2-Nitrophenyl)carbamoyl]naphthalen-2-yl Alkylcarbamates

0476280 - ÚVGZ 2018 RIV CH eng J - Článek v odborném periodiku
Goněc, T. - Straník, J. - Pesko, M. - Kos, J. - Oravec, Michal - Kralova, K. - Jampílek, J.
Photosynthesis-Inhibiting Activity of 1-[(2-Chlorophenyl)carbamoyl]- and 1-[(2-Nitrophenyl)carbamoyl]naphthalen-2-yl Alkylcarbamates.
Molecules. Roč. 22, č. 7 (2017), č. článku 1199. E-ISSN 1420-3049
Grant CEP: GA MŠMT(CZ) LO1415; GA MŠMT(CZ) EF16_013/0001609
Výzkumná infrastruktura: CzeCOS II - 90061
Institucionální podpora: RVO:67179843
Klíčová slova: alkylcarbamates * hydroxynaphthalene-carboxamides * PET inhibition * spinach chloroplasts * structure-activity relationships
Obor OECD: Biochemistry and molecular biology
Impakt faktor: 3.098, rok: 2017

Eight 1-[(2-chlorophenyl)carbamoyl]naphthalen-2-yl alkylcarbamates and eight 1-[(2-nitrophenyl)carbamoyl]naphthalen-2-yl alkylcarbamates were tested for their activity related to the inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. The PET-inhibiting activity of the compounds was relatively low, the corresponding IC50 values ranged from 0.05 to 0.664 mmol/L, and the highest activity within the series of compounds was observed for 1-[(2-chlorophenyl)-carbamoyl]naphthalen-2-yl propylcarbamate. It has been proven that the compounds are PET-inhibitors in photosystem II. Despite rather low PET-inhibiting activities, primary structure-activity trends can be discussed.
Trvalý link: http://hdl.handle.net/11104/0272815