Počet záznamů: 1
Carbonic anhydrase inhibitors and method of their production
- 1.0471686 - ÚOCHB 2017 RIV eng P - Patentový dokument
Brynda, Jiří - Cígler, Petr - Grüner, Bohumír - Maloy Řezáčová, Pavlína - Mader, P. - Šícha, Václav - Bakardjiev, Mario - Holub, Josef - Džubák, P. - Hajdúch, M.
Carbonic anhydrase inhibitors and method of their production.
2016. Vlastník: Ústav organické chemie a biochemie AV ČR, v. v. i. - Ústav molekulární genetiky AV ČR, v. v. i. - Ústav anorganické chemie AV ČR, v. v. i. - Univerzita Palackého v Olomouci. Datum udělení patentu: 22.03.2016. Číslo patentu: US9290529
Institucionální podpora: RVO:61388963 ; RVO:61388980
Klíčová slova: cancer enzyme * inhibition * carboranes
Kód oboru RIV: CE - Biochemie; CA - Anorganická chemie (UACH-T)
https://worldwide.espacenet.com/publicationDetails/biblio?CC=US&NR=9290529B2&KC=B2&FT=D&ND=4&date=20160322&DB=&locale=en_EP#
Derivatives of boron cluster compounds of general formula I and their pharmaceutically acceptable salts and solvates, and their specific inhibition effect on the enzyme carbonic anhydrase IX, a protein overexpressed in cancer tissues. Methods of synthesis and the use of the novel derivatives. These inhibitors of human carbonic anhydrase IX can be used as active compounds of pharmaceuticals for diagnostics and/or therapy of cancer diseases.
Trvalý link: http://hdl.handle.net/11104/0269504
Počet záznamů: 1