Diamond functional layers for cell-based impedance spectroscopy

0470501 - FZÚ 2017 RIV NL eng C - Konferenční příspěvek (zahraniční konf.)
Ižák, Tibor - Szabó, Ondrej - Bačáková, Lucie - Kromka, Alexander
Diamond functional layers for cell-based impedance spectroscopy.
Procedia Engineering, Vol. 168. Amsterdam: Elsevier, 2016 - (Bársony, I.; Zolnai, Z.; Battistig, G.), s. 614-617. ISSN 1877-7058.
[Eurosensors Conference /30./. EUROSENSORS 2016. Budapest (HU), 04.09.2016-07.09.2016]
Grant CEP: GA MZd(CZ) NV15-33018A
Institucionální podpora: RVO:68378271 ; RVO:67985823
Klíčová slova: polycrystalline diamond * impedance spectroscopy * biosensors
Kód oboru RIV: BM - Fyzika pevných látek a magnetismus; EI - Biotechnologie a bionika (FGU-C)

Cell-based impedance spectroscopy is a promising label-free method for electrical monitoring of cell activity in real-time. Here we present two basic designs for fabrication of diamond impedance sensors: i) fully optically transparent diamond film with hydrogen-terminated interdigitated electrodes (IDEs) and ii) built-in gold IDEs covered with a functional diamond layer (fully closed the diamond thin film or isolated nanodiamonds). We also point out technical issues for their fabrication and demonstrate their application mainly for in-vitro study of the adhesion, spreading and proliferation of cells.

Trvalý link: http://hdl.handle.net/11104/0268123