Real-time monitoring of cell activities by diamond solution-gated field effect transistors

0470495 - FZÚ 2017 RIV NL eng C - Konferenční příspěvek (zahraniční konf.)
Ižák, Tibor - Procházka, Václav - Sakata, T. - Rezek, Bohuslav - Kromka, Alexander
Real-time monitoring of cell activities by diamond solution-gated field effect transistors.
Procedia Engineering, Vol. 168. Amsterdam: Elsevier, 2016 - (Bársony, I.; Zolnai, Z.; Battistig, G.), s. 469-472. ISSN 1877-7058.
[Eurosensors Conference /30./. EUROSENSORS 2016. Budapest (HU), 04.09.2016-07.09.2016]
Grant CEP: GA ČR(CZ) GBP108/12/G108
Institucionální podpora: RVO:68378271
Klíčová slova: diamond thin film * solution-gated field effect transistor * biosensor * pH * cell cultivation * real-time monitoring
Kód oboru RIV: BM - Fyzika pevných látek a magnetismus

In this study, we present basic aspects for real-time monitoring of cell growth of human cell lines. We successfully fabricated fully optically transparent diamond-based solution-gated field effect transistor (SG-FET) on glass substrates. The diamond transistor functionalities are demonstrated by the sensitivity of electrical characteristics to solutions with different Na+ and K+ ion concentrations, and pH. Moreover, the diamond SG-FETs exhibited sensitivities to the adhesion of proteins and cells, to the cell delamination, or even to the cell death.

Trvalý link: http://hdl.handle.net/11104/0268121