Microcrystalline diamond membrane for electronic monitoring of cells in microfluidic perfusion systems

0470477 - FZÚ 2017 RIV NL eng C - Konferenční příspěvek (zahraniční konf.)
Rezek, Bohuslav - Varga, Marián - Pedrosa, C. - Chu, V. - Conde, J.P. - Kromka, Alexander
Microcrystalline diamond membrane for electronic monitoring of cells in microfluidic perfusion systems.
Procedia Engineering, Vol. 168. Amsterdam: Elsevier, 2016 - (Bársony, I.; Zolnai, Z.; Battistig, G.), s. 1442-1445. ISSN 1877-7058.
[Eurosensors Conference /30./. EUROSENSORS 2016. Budapest (HU), 04.09.2016-07.09.2016]
Grant CEP: GA ČR(CZ) GBP108/12/G108
Institucionální podpora: RVO:68378271
Klíčová slova: diamond * biosensors * impedance * cells * microfluidics * perfusion reactors
Kód oboru RIV: BM - Fyzika pevných látek a magnetismus

Self-standing microcrystalline diamond membranes were produced and embedded in three-dimensional microfluidic in-vivo-like perfusion cell culture system. Perfusion of molecules is confirmed by time-resolved fluorescent microscopy. Impedance measurements show that the diamond membranes exhibit a pronounced response to cells compared to a reference microfluidic chip without the membrane. The diamond membranes can thus be applicable as novel sensor elements in microfluidic cell reactors.

Trvalý link: http://hdl.handle.net/11104/0268115