Enantioseparations of drugs and catalysts by partial-filling affinity capillary electrophoresis using helquats as chiral selectors

0469330 - ÚOCHB 2017 CZ eng C - Konferenční příspěvek (zahraniční konf.)
Růžička, Martin - Koval, Dušan - Vávra, Jan - Reyes Gutierrez, Paul Eduardo - Teplý, Filip - Kašička, Václav
Enantioseparations of drugs and catalysts by partial-filling affinity capillary electrophoresis using helquats as chiral selectors.
Advances in Chromatography and Electrophoresis & Chiranal 2016. Olomouc: Palacký University, 2016 - (Maier, V.), s. 156-157. ISBN 978-80-244-4961-6.
[Advances in Chromatography and Electrophoresis & Chiranal 2016. Olomouc (CZ), 06.06.2016-09.06.2016]
Grant CEP: GA ČR(CZ) GA15-01948S
Institucionální podpora: RVO:61388963
Klíčová slova: affinity capillary electrophoresis * helquats * chiral selector
Kód oboru RIV: CB - Analytická chemie, separace

Noncovalent molecular interactions between helquats, a new class of dicationic helical extended diquats and selected commonly used negatively charged chiral drugs and catalysts have been investigated using partial-filling affinity capillary electrophoresis (PF-ACE). Three types of interactions of analytes with helquats were observed: (1) medium strong enantioselective interactions, (2) medium strong non-enantioselective interactions and (3) no or very weak non-enantioselective interactions.
Trvalý link: http://hdl.handle.net/11104/0267202