A Novel Model for Multicomponent Supercritical Fluid Extraction and its Application to Ruta graveolens.

0468013 - ÚCHP 2017 RIV NL eng J - Článek v odborném periodiku
Sovová, Helena - Sajfrtová, Marie - Stateva, R.P.
A Novel Model for Multicomponent Supercritical Fluid Extraction and its Application to Ruta graveolens.
Journal of Supercritical Fluids. Roč. 120, Part 1 (2017), s. 102-112. ISSN 0896-8446. E-ISSN 1872-8162
Grant CEP: GA MŠMT 2B06049
Institucionální podpora: RVO:67985858
Klíčová slova: supercritical fluid extraction * multicomponent equilibrium * kinetics
Obor OECD: Chemical process engineering
Impakt faktor: 3.122, rok: 2017

In this work, a multicomponent model for understanding the relationship between the chemical compositions of an extract and extracted plant is developed and presented for the first time. Its robustness and efficiency were validated on the example of furanocoumarins and waxes extracted from aerial parts of common rue with supercritical CO2 at pressures and temperatures (12–30) MPa and (313–333) K. For the purpose of modeling, the waxes are represented by n-tritriacontane and furanocoumarins – by xanthotoxin, the solubility of which in CO2 was measured using the dynamic method. A rigorous thermodynamic modeling framework was applied to calculate the composition-dependent solubilities of extracted compounds, which were incorporated in the kinetics model in order to calculate the extraction curves. For individual extraction curves, the average absolute deviation between the calculated and experimental extraction yields, expressed as percentage of the asymptotic extraction yield, was in the range (0.2–5.8) %.
Trvalý link: http://hdl.handle.net/11104/0267710