Structural Analysis of Natural Products

0467846 - MBÚ 2017 RIV US eng J - Článek v odborném periodiku
Přichystal, Jakub - Schug, K. A. - Lemr, Karel - Novák, Jiří - Havlíček, Vladimír
Structural Analysis of Natural Products.
Analytical Chemistry. Roč. 88, č. 21 (2016), s. 10338-10346. ISSN 0003-2700. E-ISSN 1520-6882
Grant CEP: GA MŠMT(CZ) LO1509; GA MŠMT(CZ) LH14064; GA ČR(CZ) GA16-20229S
Institucionální podpora: RVO:61388971
Klíčová slova: IONIZATION-MASS-SPECTROMETRY * BIOSYNTHETIC GENE CLUSTERS * STRUCTURE ELUCIDATION
Kód oboru RIV: EE - Mikrobiologie, virologie
Impakt faktor: 6.320, rok: 2016

Current mass spectrometry, nuclear magnetic resonance spectroscopy, and X-ray diffraction are presented as structure elucidation tools for analytical chemistry of natural products. Discovering new molecular entities combined with dereplication of known organic compounds represent prerequisites for biological assays and for respective applications as pharmaceuticals or molecular markers. Liquid chromatography is briefly addressed with respect to its use in mass spectrometry- and nuclear magnetic resonance-based metabolomics studies.
Trvalý link: http://hdl.handle.net/11104/0266200