0467331 - ÚOCHB 2017 RIV CH eng J - Článek v odborném periodiku
Lipovská, P. - Rathouská, L. - Šimůnek, O. - Hošek, J. - Kolaříková, V. - Rybáčková, M. - Cvačka, Josef - Svoboda, Martin - Kvíčala, J.
Synthesis and catalytic activity of ruthenium complexes modified with chiral racemic per- and polyfluorooxaalkanoates.
Journal of Fluorine Chemistry. Roč. 191, Nov (2016), s. 14-22. ISSN 0022-1139. E-ISSN 1873-3328
Institucionální podpora: RVO:61388963
Klíčová slova: racemic * chiral * ruthenium complex * perfluorooxaalkanoate * polyfluorooxaalkanoate
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 2.101, rok: 2016 ; AIS: 0.432, rok: 2016
DOI: https://doi.org/10.1016/j.jfluchem.2016.09.005

Silver salts of racemic 2H-perfluoro(3-oxahexanoic) (3a), perfluoro(2-methyl-3-oxahexanoic) (3b) and 2,3,3,3-tetrafluoro-2-methoxypropanoic acid (3c) gave with Hoveyda-Grubbs 2nd generation catalyst 4 or its bis(polyfiuoroalkylated) analogue 5 the corresponding bis(polyfluoroacylated) ruthenium complexes 1a-1c or 2a, 2b as mixtures of three diastereoisomers. Their catalytic activity in model ring-closing metathesis (RCM) reactions decreased in the order 1b-2b > 1a-2a > 1c due to increased steric hindrance around the catalytic centre in complexes 1a, 1c and 2a, as well as due to lower acidity of acid 3c resulting in lower electrophilicity of the complex 1c. Thus, the complexes 1b and 2b displayed high activity in RCM of bis-unsaturated malonates forming disubstituted (RCM2) or trisubstituted (RCM3) double bond and were even significantly active in the formation of tetrasubstituted bond (RCM4), while complexes 1a, 1c were active in RCM2 but inactive in RCM3. Moreover, the yield of RCM2 catalyzed with complex is was rather low.
Trvalý link: http://hdl.handle.net/11104/0265450