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Intracellular fate of inhaled cadmium oxide nanoparticles and their effect on target organs of mice
- 1.0467278 - ÚIACH 2017 SG eng A - Abstrakt
Mikuška, Pavel - Večeřa, Zbyněk - Buchtová, Marcela - Dumková, J. - Vrlíková, Lucie - Putnová, Barbora - Dočekal, Bohumil - Čapka, Lukáš - Coufalík, Pavel - Křůmal, Kamil - Fictum, P. - Hampl, A.
Intracellular fate of inhaled cadmium oxide nanoparticles and their effect on target organs of mice.
11. th International Particle Toxicology Conference. Book of Abstracts. 2016. s. 124-124.
[International Particle Toxicology Conference /11./. 26.09.2016-30.09.2016, Singapore]
Grant CEP: GA ČR(CZ) GAP503/11/2315; GA ČR(CZ) GBP503/12/G147; GA ČR(CZ) GA14-25558S
Institucionální podpora: RVO:68081715 ; RVO:67985904
Klíčová slova: nanoparticles * inhalation * mice
Kód oboru RIV: CB - Analytická chemie, separace; EB - Genetika a molekulární biologie (UZFG-Y)
Contribution summarizes findings obtained during inhalation experiments performed with mice for 6 weeks. Inhalation of CdO nanoparticles results in their accumulation not only in the organ of entry, the lungs, but they were also transported by blood to other organs causing serious damage at tissue as well as at cellular level. The exposure to high doses of such nanoparticles leads to complex symptoms affecting the entire body.
Trvalý link: http://hdl.handle.net/11104/0265415
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