Data on cytochrome c oxidase assembly in mice and human fibroblasts or tissues induced by SURF1 defect

0466616 - FGÚ 2017 RIV DE eng J - Článek v odborném periodiku
Kovářová, Nikola - Pecina, Petr - Nůsková, Hana - Vrbacký, Marek - Zeviani, M. - Mráček, Tomáš - Viscomi, C. - Houštěk, Josef
Data on cytochrome c oxidase assembly in mice and human fibroblasts or tissues induced by SURF1 defect.
Data in Brief. Roč. 7, June 01 (2016), s. 1004-1009. ISSN 2352-3409
Grant CEP: GA ČR(CZ) GB14-36804G; GA MŠMT(CZ) LL1204; GA MZd(CZ) NT12370
Institucionální podpora: RVO:67985823
Klíčová slova: cytochrome c oxidase * respiratory chain * SURF1 * knockout * doxycycline
Obor OECD: Human genetics

This paper describes data related to a research article entitled “Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects”. This paper includes data of the quantitative analysis of individual forms of respiratory chain complexes I, III and IV present in SURF1 knockout (SURF1−/−) and control (SURF1+/+) mouse fibroblasts and tissues and in fibroblasts of human control and patients with SURF1 gene mutation. Also it includes data demonstrating response of complex IV, cytochrome c oxidase (COX), to reversible inhibition of mitochondrial translation in SURF1−/− mouse and SURF1 patient fibroblast cell lines.
Trvalý link: http://hdl.handle.net/11104/0264887