Crimean-Congo Hemorrhagic Fever Virus in Bulgaria and Turkey

0463249 - ÚBO 2017 RIV US eng J - Článek v odborném periodiku
Mertens, M. - Schuster, I. - Sas, M. A. - Vatansever, Z. - Hubálek, Zdeněk - Güven, E. - Deniz, A. - Georgiev, G. - Peshev, R. - Groschup, M. H.
Crimean-Congo Hemorrhagic Fever Virus in Bulgaria and Turkey.
Vector-Borne and Zoonotic Diseases. Roč. 16, č. 9 (2016), s. 619-623. ISSN 1530-3667. E-ISSN 1557-7759
GRANT EU: European Commission(XE) 261504 - EDENEXT
Institucionální podpora: RVO:68081766
Klíčová slova: Crimean-Congo hemorrhagic fever virus: CCHFV * domestic animals * ELISA * epidemiology
Kód oboru RIV: GJ - Choroby a škůdci zvířat, veterinární medicína
Impakt faktor: 2.045, rok: 2016

Infections of humans with the tick-borne Crimean-Congo hemorrhagic fever virus (CCHFV) can cause a severe hemorrhagic fever with case fatality rates of up to 80%. Most humans are infected by tick bite, crushing infected ticks by hand or by unprotected contact with blood of viremic mammals. Next to the notified human CCHF cases, the real distribution and the situation in animals in Southeastern Europe are nearly unknown. Since domestic ruminants play a crucial role in the life cycle of the vector ticks and the transmission and amplification of the virus, the antibody prevalence in those animals is a good indicator for the presence of CCHFV in a region. Therefore, the prevalence of CCHFV-specific antibodies was investigated in domestic ruminants of different regions of Bulgaria and Turkey. Sera of 1165 ruminants were tested and a prevalence of up to 90% was identified. The overall prevalence for Bulgaria was 26% and for Turkey 57%. The results highlight the risk of human infections in those regions and the importance of the investigation of the prevalence in animals for identification of risk areas. This article provides a unique overview about published CCHFV antibody prevalence in animals in comparison to human incidences in different areas of Bulgaria and Turkey. Although it will help to complete the understanding of the CCHFV situation in these countries, it also demonstrates the lack of unpublished and published data even in these highly endemic areas.
Trvalý link: http://hdl.handle.net/11104/0262488