Effect of Colloidal Silica Dioxide on Rheological Properties of Common Pharmaceutical Excipients.

0462458 - ÚCHP 2017 CZ eng C - Konferenční příspěvek (zahraniční konf.)
Majerová, D. - Tran, D.T. - Kulaviak, Lukáš - Růžička, Marek - Štěpánek, F. - Zámostný, P.
Effect of Colloidal Silica Dioxide on Rheological Properties of Common Pharmaceutical Excipients.
Abstracts. -: -, 2016, F4.3. ISBN N.
[International Conference on Process Integration, Modeling and Optimization for Energy Savings and Pollution Reduction (PRES) /19./. Prague (CZ), 27.08.2016-31.08.2016]
Institucionální podpora: RVO:67985858
Klíčová slova: rheological properties * pharmaceutical excipients * comparison
Kód oboru RIV: CI - Průmyslová chemie a chemické inženýrství

In this work, the rheological properties of silicified microcrystalline cellulose and pregelatinized starch was investigated in comparison to the characteristics of pure excipients. At first, pure materials were analysed on scanning electron microscopy (SEM) to obtain their particle size distribution and particle shape. Also the rheological properties of all three substances were examined by the Freeman FT4 rheometer. The observed properties were in accordance with known characteristics and typical behaviour of the excipients.
Trvalý link: http://hdl.handle.net/11104/0261924