Počet záznamů: 1
From simple to supercomplex: mitochondrial genomes of euglenozoan protists
- 1.0461890 - BC 2017 RIV GB eng J - Článek v odborném periodiku
Faktorová, Drahomíra - Dobáková, Eva - Peña-Diaz, Priscila - Lukeš, Julius
From simple to supercomplex: mitochondrial genomes of euglenozoan protists.
F1000Research. Roč. 5, 15 NOV (2016), č. článku 392. ISSN 2046-1402
Grant CEP: GA ČR GA15-21974S
Institucionální podpora: RVO:60077344
Klíčová slova: euglenozoa * mitochondria * mitochondrial genome
Kód oboru RIV: EB - Genetika a molekulární biologie
Mitochondria are double membrane organelles of endosymbiotic origin, best known for constituting the centre of energetics of a eukaryotic cell. They contain their own mitochondrial genome, which as a consequence of gradual reduction during evolution typically contains less than two dozens of genes. In this review, we highlight the extremely diverse architecture of mitochondrial genomes and mechanisms of gene expression between the three sister groups constituting the phylum Euglenozoa - Euglenida, Diplonemea and Kinetoplastea. The earliest diverging euglenids possess a simplified mitochondrial genome and a conventional gene expression, whereas both are highly complex in the two other groups. The expression of their mitochondrial-encoded proteins requires extensive post-transcriptional modifications guided by complex protein machineries and multiple small RNA molecules. Moreover, the least studied diplonemids, which have been recently discovered as a highly abundant component of the world ocean plankton, possess one of the most complicated mitochondrial genome organisations known to date.
Trvalý link: http://hdl.handle.net/11104/0267774
Počet záznamů: 1