The Drosophila chitinase-like protein IDGF3 is involved in protection against nematodes and woung healing

0458494 - BC 2017 RIV CH eng J - Článek v odborném periodiku
Kučerová, Lucie - Brož, Václav - Arefin, B. - Maaroufi, H. O. - Hurychová, J. - Strnad, Hynek - Žurovec, Michal - Theopold, U.
The Drosophila chitinase-like protein IDGF3 is involved in protection against nematodes and woung healing.
Journal of Innate Immunity. Roč. 8, č. 2 (2016), s. 199-210. ISSN 1662-811X. E-ISSN 1662-8128
Grant CEP: GA ČR GA14-27816S
Institucionální podpora: RVO:60077344 ; RVO:68378050
Klíčová slova: chitinase-like proteins * imaginal disc growth factor * hemolymph clot
Kód oboru RIV: CE - Biochemie; EB - Genetika a molekulární biologie (UMG-J)
Impakt faktor: 3.938, rok: 2016
http://www.karger.com/Article/FullText/442351

We describe a novel function of Drosophila Imaginal Disc Growth Factor 3 (IDGF3), as being a regulator of wound healing and a component of the clot formed after wounding. We show that it has an immune-protective role during entomopathogenic nematode (EPN) infections.

Trvalý link: http://hdl.handle.net/11104/0258766