The contribution of intracranial eeg to research on the empathy for pain

0456444 - ÚPT 2016 IE eng A - Abstrakt
Brázdil, M. - Riecanski, I. - Roman, R. - Chládek, Jan - Mareček, R. - Shaw, D. J. - Lamm, C.
The contribution of intracranial eeg to research on the empathy for pain.
Clinical Neurophysiology. Elsevier. Roč. 126, č. 3 (2015), e35. ISSN 1388-2457. E-ISSN 1872-8952.
[Congress of the Czech and Slovak Society of Clinical Neurophysiology /61./. 15.10.2015-18.10.2015, Olomouc]
Institucionální podpora: RVO:68081731
Klíčová slova: bilateral anterior insular cortex * medial/anterior cingulate cortex * pain * empathy * ERP * intracranial * intracerebral * subdural * EEG
Kód oboru RIV: BH - Optika, masery a lasery

Bilateral anterior insular cortex and medial/anterior cingulate cortex seem to play a crucial role in empathy for another person´s pain, but several other brain regions are also co-activated. Electrophysiological pain-empathy responses have been analysed to investigate the temporal dynamics of neural activity underlying this process. In the present study, we investigated intracranial event-related brain potentials (ERPs) from three intractable epileptic patients who underwent preoperatively diagnostic invasive video-EEG monitoring. During the experiment, patients watched 3-second dynamic visual stimuli depicting needle injections into a left hand, or the same left hand touched by a cue tip. Intracranial EEGs were recorded using intracerebral and subdural electrodes, investigating in total more than 300 brain sites. The ERPs in each condition (needle and cue tip) were averaged separately off-line, and statistical differences in response amplitudes after painful vs. non-painful stimuli were detected. In all three subjects, significantly different event-related responses to painful vs. non-painful stimuli were observed in some investigated neural structures, including left-hemispheric temporo-parietal junction, right-sided temporo-occipital junction, and right-sided lateral occipital cortex. In these brain sites, painful needle stimuli evoked more prominent ERPs compared to cue-tip touch.
Trvalý link: http://hdl.handle.net/11104/0256978