Diamond coated quartz crystal microbalance sensor for detection of protein adsorption

0455041 - FZÚ 2016 RIV CZ eng A - Abstrakt
Procházka, Václav - Kulha, P. - Ižák, Tibor - Ukraintsev, Egor - Varga, Marián - Kromka, Alexander
Diamond coated quartz crystal microbalance sensor for detection of protein adsorption.
Workshop of Physical Chemists and Electrochemists /15./. Book of abstracts. Brno: Masaryk University, 2015 - (Trnková, L.). s. 142-144. ISBN 978-80-210-7857-4.
[Workshop of Physical Chemists and Electrochemists /15./. 26.05.2015-27.05.2015, Brno]
Grant CEP: GA ČR(CZ) GBP108/12/G108
Institucionální podpora: RVO:68378271
Klíčová slova: diamond * biosensors * protein * QCM * impedance spectroscopy
Kód oboru RIV: BM - Fyzika pevných látek a magnetismus

In this study, we present a sensor based on a bulk acoustic quartz crystal microbalance (QCM) piezoelectric device coated with nanocrystalline diamond (NCD) as a sensitive layer for detection of adsorbed proteins. Three kinds of proteins were tested (FBS, BSA, FN). The higher frequency shift in serial resonance almost 650 Hz was observed for sensor with double side FBS coating. Moreover, oxygen terminated surfaces exhibited higher shift in frequency for single side covered QCM sensors, than the hydrogenated surfaces.
Trvalý link: http://hdl.handle.net/11104/0255691