Rheological and electrical properties of polymeric nanoparticle solutions and their influence on RBC suspensions

0453826 - ÚH 2016 BG eng C - Konferenční příspěvek (zahraniční konf.)
Antonova, N. - Ivanov, I. - Mitova, V. - Kowalczuk, A. - Říha, Pavel
Rheological and electrical properties of polymeric nanoparticle solutions and their influence on RBC suspensions.
Smart and green interfaces: Fundamentals and diagnostics. Sofia: Bulgarian Academy of Sciences, 2015, s. 48.
[Symposium Smart and Green Interfaces: Fundamentals and Diagnostics 2015. Sofia (BG), 29.10.2015-31.10.2015]
Grant ostatní: COST- European Cooperation in Science and Technology(BG) MP1106
Program: COST Actions
Institucionální podpora: RVO:67985874
Klíčová slova: RBC suspensions * poly(acrylic acid) nanoparticles * rheology
Kód oboru RIV: BK - Mechanika tekutin

The aim of the work was to study the influence of structure, shape, concentration and molecular weight of three different types of nanoparticles: a new core–shell type star, linear and micelles polymeric nanoparticles of poly(acrylic acid) on blood and RBC suspensions rheological behavior. The studied different types of nanoparticles suspended in 0.9% NaCl solutions were added to RBC suspensions: (i) a new core–shell type star polymer whose interior forms hyperbranched polystyrene bearing arms of poly(acrylic acid) with molecular weight M_n=56 920 kDa (AK); (ii) linear polyacrylic chains with average molecular weights M_n=225000, 20000 and 6000 (PAA); (iii) polymeric micelles with a mixed shell. The obtained results showed that the addition of nanoparticles decreases the apparent viscosity and increases the electrical conductivity of RBC suspensions. The potential use of nanoparticles for a drug delivery is discussed with respect to their effect on rheological and electrical properties of blood.
Trvalý link: http://hdl.handle.net/11104/0255313