Ecology of malaria infections in western lowland gorillas/ninhabiting Dzanga Sangha Protected Areas, Central African/nRepublic

0453432 - BC 2016 RIV GB eng J - Článek v odborném periodiku
Mapua, M. I. - Qablan, M. A. - Pomajbíková, Kateřina - Petrželková, Klára Judita - Hůzová, Z. - Rádrová, Jana - Votýpka, Jan - Todd, A. - Jirků, Milan - Leendertz, F. H. - Lukeš, Julius - Neel, C. - Modrý, David
Ecology of malaria infections in western lowland gorillas/ninhabiting Dzanga Sangha Protected Areas, Central African/nRepublic.
Parasitology. Roč. 142, č. 7 (2015), s. 890-900. ISSN 0031-1820. E-ISSN 1469-8161
Institucionální podpora: RVO:60077344
Klíčová slova: African great apes * malaria * lowland gorilla * Plasmodium spp.
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 3.031, rok: 2015

African great apes are susceptible to infections with several species of Plasmodium, including the predecessor of Plasmodium falciparum. Little is known about the ecology of these pathogens in gorillas. A total of 131 gorilla fecal samples were collected from Dzanga-Sangha Protected Areas to study the diversity and prevalence of Plasmodium species. The effects of sex and age as factors influencing levels of infection with Plasmodium in habituated gorilla groups were assessed. Ninety-five human blood samples from the same locality were also analysed to test for cross-transmission between humans and gorillas. According to a cytB PCR assay 32% of gorilla's fecal samples and 43.1% human individuals were infected with Plasmodium spp. All Laverania species, Plasmodium vivax, and for the first time Plasmodium ovale were identified from gorilla samples. Plasmodium praefalciparum was present only from habituated individuals and P. falciparum was detected from human samples. Although few P. vivax and P. ovale sequences were obtained from gorillas, the evidence for cross-species transmission between humans and gorillas requires more in depth analysis. No association was found between malaria infection and sex, however, younger individuals aged 6 years were more susceptible. Switching between two different Plasmodium spp. was observed in three individuals. Prolonged monitoring of Plasmodium infection during various seasons and recording behavioural data is necessary to draw a precise picture about the infection dynamics.
Trvalý link: http://hdl.handle.net/11104/0254276