Calretinin and parvalbumin immunoreactive interneurons in the retrosplenial cortex of the rat brain: Qualitative and quantitative analyses

0452629 - FGÚ 2016 RIV NL eng J - Článek v odborném periodiku
Salaj, M. - Druga, Rastislav - Cerman, J. - Kubová, Hana - Barinka, F.
Calretinin and parvalbumin immunoreactive interneurons in the retrosplenial cortex of the rat brain: Qualitative and quantitative analyses.
Brain Research. Roč. 1627, Nov 19 (2015), s. 201-215. ISSN 0006-8993. E-ISSN 1872-6240
Grant CEP: GA ČR(CZ) GBP304/12/G069
Institucionální podpora: RVO:67985823
Klíčová slova: retrosplenial cortex * calretinin * parvalbumin * interneurons * calcium-binding proteins * perirhinal cortex
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 2.561, rok: 2015

The retrosplenial cortex (RSC) is a mesocortical region broadly involved with memory and navigation. It shares many characteristics with the perirhinal cortex (PRC), both of which appear to be significantly involved in the spreading of epileptic activity.).
Compared to PRC, RSC was observed to have a higher intensity of parvalbumin (PV) staining and lower intensity of calretinin (CR) staining of neuropil. Vertically-oriented bipolar neurons were the most common morphological type among CR+ neurons. The staining pattern did not allow for a similarly detailed analysis of somatodendritic morphology of PV+ neurons. RSC possessed lower absolute (i.e., neurons/mm3) and relative (i.e., percentage of the overall neuronal population) densities of CR+ neurons and similar absolute and lower relative densities of PV+ neurons relative to PRC

Trvalý link: http://hdl.handle.net/11104/0253579