Počet záznamů: 1  

Alpha and beta power decrease during enhanced cognitive eff ort in the basal ganglia: An intracerebral recording study

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    0452198 - ÚPT 2016 CZ eng A - Abstrakt
    Bočková, M. - Chládek, Jan - Jurák, Pavel - Halámek, Josef - Rapcsak, S. Z. - Baláž, M. - Chrastina, J. - Rektor, I.
    Alpha and beta power decrease during enhanced cognitive eff ort in the basal ganglia: An intracerebral recording study.
    15th European Congress on Clinical Neuro­physiology. Book of Abstracts. Brno: Česká a slovenská společnost pro klinickou neurofyziologii, 2015. s. 33.
    [European Congress on Clinical Neuro­physiology /15./. 30.09.2015-04.10.2015, Brno]
    Grant CEP: GA MŠMT(CZ) LO1212
    Institucionální podpora: RVO:68081731
    Klíčová slova: deep brain stimulation * STN * GPi * Parkinson´s disease * ERD * ERS * complex cognitive functions
    Kód oboru RIV: FA - Kardiovaskulární nemoci vč. kardiochirurgie

    Cognitive adverse eff ects may accompany deep brain stimulation (DBS) treatment, as the basal ganglia have influence on widespread neocortical networks. The aim of this study was to investigate how complex motor-cognitive activities are processed in the subthalamic nucleus (STN) and internal globus pallidum (GPi). Dystonia patients implanted with GPi-DBS electrodes and individuals with Parkinson´s disease (PD) or essential tremor with STN-DBS electrodes performed two tasks involving the writing of single letters: 1. copying letters from a monitor; and 2. writing of any letter other than that appearing on the monitor. The cognitive load of the second task was increased relative to the first. Local event-related alpha and beta desynchronizations (ERD) were more expressed during the second task while the lower gamma synchronization (ERS) decreased regardless of the basal ganglia structure from which recordings were obtained or the clinical diagnosis. Task-related ERD differences recorded from the language-dominant left hemisphere correlated with a behavioural (RT) measure of cognitive effort. ERD changes declined after levodopa intake in PD patients. The STN and Gpi participate in cognitive networks. Alpha and beta ERD seems to be essential during processing complex motor-cognitive tasks and increases with enhanced cognitive effort.
    Trvalý link: http://hdl.handle.net/11104/0253226

     
     
Počet záznamů: 1  

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