Semi-automatic motion compensation of contrast-enhanced ultrasound images from abdominal organs for perfusion analysis

0450646 - ÚPT 2016 RIV GB eng J - Článek v odborném periodiku
Schafer, S. - Nylund, K. - Saevik, F. - Engjom, T. - Mézl, M. - Jiřík, Radovan - Dimcevski, G. - Gilja, O.H. - Tönnies, K.
Semi-automatic motion compensation of contrast-enhanced ultrasound images from abdominal organs for perfusion analysis.
Computers in Biology Medicine. Roč. 63, AUG 1 (2015), s. 229-237. ISSN 0010-4825. E-ISSN 1879-0534
Grant CEP: GA ČR GAP102/12/2380
Institucionální podpora: RVO:68081731
Klíčová slova: ultrasonography * motion analysis * motion compensation * registration * CEUS * contrast-enhanced ultrasound * perfusion * perfusion modeling
Kód oboru RIV: FS - Lékařská zařízení, přístroje a vybavení
Impakt faktor: 1.521, rok: 2015

This paper presents a system for correcting motion influences in time-dependent 2D contrast-enhanced ultrasound (CEUS) images to assess tissue perfusion characteristics. The system consists of a semiautomatic frame selection method to find images with out-of-plane motion as well as a method for automatic motion compensation. Translational and non-rigid motion compensation is applied by introducing a temporal continuity assumption. A study consisting of 40 clinical datasets was conducted to compare the perfusion with simulated perfusion using pharmacokinetic modeling. Overall, the proposed approach decreased the mean average difference between the measured perfusion and the pharmacokinetic model estimation. It was non-inferior for three out of four patient cohorts to a manual approach and reduced the analysis time by 41% compared to manual processing.
Trvalý link: http://hdl.handle.net/11104/0251950