Candida parapsilosis Biofilm Identification by Raman Spectroscopy

0441095 - ÚPT 2015 RIV CH eng J - Článek v odborném periodiku
Samek, Ota - Mlynariková, K. - Bernatová, Silvie - Ježek, Jan - Krzyžánek, Vladislav - Šiler, Martin - Zemánek, Pavel - Růžička, F. - Holá, Miroslava - Mahelová, M.
Candida parapsilosis Biofilm Identification by Raman Spectroscopy.
International Journal of Molecular Sciences. Roč. 15, č. 12 (2014), s. 23924-23935. E-ISSN 1422-0067
Grant CEP: GA MŠMT(CZ) LO1212; GA MŠMT ED0017/01/01; GA ČR GAP205/11/1687
Institucionální podpora: RVO:68081731
Klíčová slova: Raman spectroscopy * Candida parapsilosis * biofilm
Kód oboru RIV: BH - Optika, masery a lasery
Impakt faktor: 2.862, rok: 2014

Colonies of Candida parapsilosis on culture plates were probed directly in situ using Raman spectroscopy for rapid identification of specific strains separated by a given time intervals (up to months apart). To classify the Raman spectra, data analysis was performed using the approach of principal component analysis (PCA). The analysis of the data sets generated during the scans of individual colonies reveals that despite the inhomogeneity of the biological samples unambiguous associations to individual strains (two biofilm-positive and two biofilm-negative) could be made.
Trvalý link: http://hdl.handle.net/11104/0244155