Sex differences in methamphetamine pharmacokinetics in adult rats and its transfer to pups through the placental membrane and breast milk

0439588 - FGÚ 2015 RIV IE eng J - Článek v odborném periodiku
Rambousek, Lukáš - Kačer, P. - Syslová, K. - Bumba, J. - Bubeníková-Valešová, V. - Šlamberová, R.
Sex differences in methamphetamine pharmacokinetics in adult rats and its transfer to pups through the placental membrane and breast milk.
Drug and Alcohol Dependence. Roč. 139, JUN (2014), s. 138-144. ISSN 0376-8716. E-ISSN 1879-0046
Institucionální podpora: RVO:67985823
Klíčová slova: methamphetamine * amphetamine * pharmacokinetics * sex differences * breast feeding milk * mass spectrometry
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 3.423, rok: 2014

We demonstrated that female rats display higher levels of methamphetamine (METH) and amphetamine (AMP), thus indicating a greater risk of addiction and toxicity. Furthermore, our data show that pups are exposed to both METH and AMP following dam exposure
Trvalý link: http://hdl.handle.net/11104/0242901