High-frequency electromagnetic radiation and the production of free radicals in four mouse organs

0438727 - ÚACH 2015 RIV SK eng J - Článek v odborném periodiku
Barcal, J. - Stopka, Pavel - Křížová, Jana - Vrba, J. - Vožeh, F.
High-frequency electromagnetic radiation and the production of free radicals in four mouse organs.
Activitas Nervosa Superior Rediviva. Roč. 56, 1-2 (2014), s. 9-14. ISSN 1337-933X
Institucionální podpora: RVO:61388980
Klíčová slova: Free radicals * Mobile phones * Paramagnetic resonance spectroscopy * Radiation
Kód oboru RIV: CA - Anorganická chemie

The study was designed to evaluate the effect of high-frequency electromagnetic field (HF EMF) 900 MHz on reactive oxygen species (free radicals) production. The experimental animals (10 mice of C3H strain) were exposed to whole-body irradiation over 14 days (3 hours daily) in a special exposure chamber with the possibility of a specific absorption rate measurement. The 10 control animals were kept in an analogous position (inside the chamber) but in turn-offmode. After the last exposure, four tissue samples (brain, liver, heart, kidney) were immediately stored in liquid nitrogen and transported to a special electron paramagnetic (spin) resonance spectroscopy measurement. In all four tissue samples of irradiated animals, a statistically significant increase (p < 0.0025) of hydroxyl radicals concentration was found. These results confirm previous experiments with indirect assessment of free radicals overproduction (made by enzymatic systems depiction) and strongly support the hypothesis about the possible mechanism and/or harmful effect of long-term HF EMF exposure.
Trvalý link: http://hdl.handle.net/11104/0242155