Molecular characterization, tissue distribution, and ultrastructural localization of adipokinetic hormones in the CNS of the firebug Pyrrhocoris apterus (Heteroptera, Insecta)

0437332 - BC 2015 RIV US eng J - Článek v odborném periodiku
Kodrík, Dalibor - Stašková, Tereza - Jedličková, V. - Weyda, F. - Závodská, Radka - Pflegerová, Jitka
Molecular characterization, tissue distribution, and ultrastructural localization of adipokinetic hormones in the CNS of the firebug Pyrrhocoris apterus (Heteroptera, Insecta).
General and Comparative Endocrinology. Roč. 210, Jan 1 (2015), s. 1-11. ISSN 0016-6480. E-ISSN 1095-6840
Grant CEP: GA ČR GA14-07172S
Institucionální podpora: RVO:60077344
Klíčová slova: AKH * pre-pro-hormone * insect brain
Kód oboru RIV: ED - Fyziologie
Impakt faktor: 2.667, rok: 2015
http://www.sciencedirect.com/science/article/pii/S0016648014004158

In this paper we studied the nucleotide sequence, tissue distribution, and subcellular localization of adipokinetic hormones (AKHs) in the brain and CC of the firebug Pyrrhocoris apterus. In situ hybridization and q-RT-PCR revealed the expression of their genes not only in the CC, but also in brain. Electron microscopy analysis of the brain revealed the presence of these hormones in specialized secretory granules localized predominantly in the cellular bodies of neurons. The hormones might be transported from the granules into the axons, where they could play a role in neuronal signalling. Under acute stress the level of AKHs in the brain increased to a greater extent than that in the CC.
Trvalý link: http://hdl.handle.net/11104/0243774