Bioavailability and Antioxidant Activity of Black Chokeberry (Aronia melanocarpa) Polyphenols: in vitro and in vivo Evidences and Possible Mechanisms of Action: A Review

0436844 - BFÚ 2015 RIV US eng J - Článek v odborném periodiku
Denev, P. - Kratchanov, C.G. - Číž, Milan - Lojek, Antonín - Kratchanova, M.
Bioavailability and Antioxidant Activity of Black Chokeberry (Aronia melanocarpa) Polyphenols: in vitro and in vivo Evidences and Possible Mechanisms of Action: A Review.
Comprehensive Reviews in Food Science and Food Safety. Roč. 11, č. 5 (2012), s. 471-489. ISSN 1541-4337. E-ISSN 1541-4337
Institucionální podpora: RVO:68081707
Klíčová slova: Antioxidant activity * Aronia melanocarpa * bioavailability
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 5.053, rok: 2012

Black chokeberry (Aronia melanocarpa) is a distinctive berry with a high content of polyphenol compounds and possesses one of the highest in vitro antioxidant activities among fruits. The bioavailability of aronia polyphenols seems to be low, but there is ample evidence for chokeberry health benefits including antidiabetic, cardioprotective, hepatoprotective, antimutagenic, and anticarcinogenic effects. This review presents the available information for the bioavailability and antioxidant activity of chokeberry polyphenols and explains the possible mechanisms of action in vivo in the prevention and treatment of oxidative stress-related diseases. The review shows the available data for chokeberry antioxidant activity in vitro, in isolated cells and cell lines, and in vivo, in both human subjects and animals. It is evident that in vivo antioxidant action of chokeberry extends far beyond radical scavenging and includes suppression of reactive oxygen and nitrogen species formation, inhibition of prooxidant enzymes, restoration of antioxidant enzymes, and probably cellular signaling to regulate the level of antioxidant compounds and enzymes.
Trvalý link: http://hdl.handle.net/11104/0240498